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Abstract
The aim of this study was to determine the effects of a medicinal plants extracted containing Achyranthes aspera (50%), Tithonia diversifolia (20%), Pseuderanthemum palatiferum (20%), and Polyscias fruticosa (10%) on biochemical and hematological parameters, and disease resistance of growing pigs. Forty-five weaned pigs were feed basal diet and medicinal plants extract mixture as an additive at levels of 0.5 (M-0,5); 1.0 (M-1,0); and 1.5 g (M-1,5) in 1.0 kg of fed; Negative control (NC): Basal diet, positive control (PC): Basal diet plus colistin antibiotic (1g/kg basal diet three pig per treatment and 3 replications. The results showed that, the bilirubin-direct in the M-0,5 group (0,9 µmol/L); bilirubin-indirect in the M-1,5 group (2,3 µmol/L) were higher than that in the control groups. Cholesterol concentration and LDL-C in the treatment groups were higher than that in the NC group (p < 0.05). MCV and MCH value in the M-1,5 group were higher than the M-1,0 group; but lower than NC group. There were no significant differences in bacterial (E. coli, Salmonella) population in feces (p < 0.05). The ratio of diarrhea tended to decrease when increasing the level of medicinal plants mixture: NC group (7.35 % animal day), M-0.5 (5.14 % animal day), M-1.0 (4.96 % animal day), and M-1.5 (4.31 % animal day). Thus, adding a mixture of medicinal plants in fed might increase the number of WBC, bilirubin-direct, bilirubin-indirect; increased the MCV and MCH value; and decreased the ratio of diarrhea in growing pig.